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Hayem-Widal disease (Georges Fernand Isidore Widal)
Also known as:
Abrami's disease
Abrami's syndrome
Dreyfus-Dausset-Widal syndrome
Dyke-Young syndrome (chronic macrocytic type)
Hayem's anaemia
Hayem's icterus
Hayem-Widal syndrome
Hayem-Widal-Loutit syndrome
Lederer-Brill syndrome
Lederer’s anaemia (acute transient type)
Widal's disease
Widal’s syndrome
Widal, Abrami and Brulé haemolytic icterus
Widal-Ravaut disease
Associated persons:
Pierre Abrami
Nathan Edwin Brill
Unknown Brulé
Jean Dausset
B. Dreyfus
Sidney Campbell Dyke
Georges Hayem
John Freeman Loutit
Paul Ravaut
Georges Fernand Isidore Widal
Frieda Young
Description:
A now obsolete term for a haematological disorder clinically characterised by decreased red blood count, spherocytosis, icterus, and splenomegaly. The erythrocytes are formed normally but are destroyed prematurely as a result of haemolytic processes. Slightly more prevalent in females; onset at all ages. Extremely variable clinical features. The term Hayem-Widal is now generally being replaced by «acquired haemolytic anaemia.»
See also:
Dyke-Young syndrome - a chronic macrocytic type of anaemia, under Sidney Campbell Dyke, English pathologist, born 1886.
Lederer-Brill disease - acute febrile hemolytic anaemia, under Max Lederer, American pathologist, 1885-1952.
Loutit’s syndrome - haemolytic jaundice, under John Freeman Loutit, British physician, born 1910.
Bibliography:
- G. Hayem:
Sur une variété particulière d’ictère chronique. Ictère infectieux chronique splénomégalique.
La presse médicale, Paris, 1898, 6: 121-125.
Sur une variété particulière d’ictère chronique splénomégalique.
J Méd intern., 1898, 2: 116-118.
- F. Widal, P. Ravaut:
Ictère chronique acholurique congénital chez un homme de vingt-neuf ans.
Bulletins et memoires de la Société medicale des hôpitaux de Paris, 1902, 19: 984-991.
- F. Widal, P. Abrami:
Ictère hémolytique non congénitaux avec anémie. Recherches de la résistance globulaire par la procédé de hématises déplasmatisées.
La presse médicale, Paris, 1907, 15: 749.
divers d’ictère hémolytiques non congénitaux, avec anémie; la recherche de la résistance glubulaire par le procédé des hématies déplasmatisées.
Bulletins et memoires de la Société medicale des hôpitaux de Paris, 1907, 24: 1127-1169.
- B. Dreyfus, J. Dausset, G. Widal:
Étude clinique et hématologique de douze cas d’anémie hémolytique acquise avec anti corps.
Revue d'hématologie, 1951, 6: 349.
- J. V. Dacie, P. L. Mollison, N. Richardson, et al:
Atypical congenital haemolytic anaemias.
Clinical Immunology and Allergy. London, Philadelphia, Baillière Tindall, 1987. Volume 1, p 251.
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