- A dictionary of medical eponyms

Boeck's sarcoid

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A generalized benign systemic granulomatous disease most frequently involving the lymph nodes, liver, skin, lungs, spleen, salivary glands, and eyes. More frequent in young adults 20 to 30 years of age, with a predilection for females. In the U.S.A. it occurs frequently in Negroes. Etiology unknown.

The English physician Robert Willan in 1808 described erythema nodosum, another skin symptom that in 1946 was proved to be related also to sarcoidosis. The skin lesions were described first by Sir Jonathan Hutchinson in 1877 and later by Ernest Henri Besnier in 1889. Boeck in 1899 described the first case of sarcoidosis with skin changes and general destruction of lymph nodes. Involvement of other parts of the body was reported by Jörgen Nilsen Schaumann to the Societé française de Dermatologie et de Syphiligraphie pour le Prix Zambaco, in 1914. Through his paper of 1916-1917) the systemic nature of sarcoidosis came to be recognized. The histological picture of lupus pernio with presence of epithelid cells and giant cells was first described in 1892 by the two French physicians H. Tenneson and Charles Eugene Quinquaud (1841-1894). Alexander Bittorf (1876-1940), Erich Kusnitzky (1883-1960) in 1915 drew attention to the pulmonary manifestation of sarcoidosis. The Norwegian pathologist Morten Ansgar Kveim (1892-1966) in 1941 published a test to differentiate sarcoidosis from tuberculosis. Danbolt in 1947 re-examined Boeck’s original patient, then aged 80.


  • R. Willan:
    On Cutaneous Diseases.
    London, J. Johnson, 1796-1808. Volume 1.
  • J. Hutchinson:
    Case of livid papillary psoriasis.
    In his: Illustrations of Clinical surgery. Volume 1. London, J and A Churchill, 1877. Page 42. On eruptions which occur in connection with gout. Mortimer’s malady.
    Archives of Surgery, London, 1898, 9: 307, 315.
  • E. Besnier:
    Lupus pernio de la face; synovites fongueuses (scrofulo-tuberculeuses) symétriques des extrémités superieures.
    Annales de dermatologie et de syphilographie, Paris, 1889; 2nd series; 10: 333-336.
  • H. Tenneson, C. E. Quinquaud:
    Lupus pernio.
    Annales de Dermatologie et de Syphiligraphie, Paris, 1892, 3: 142-144.
  • C. P. M. Boeck:
    Multipelt beningt hud-sarcoi. Med 4 tavler. (En hidtil ikke beskreven hudaffektion.
    Norsk Magazin for Lægevidenskaben, Kristiania (Oslo), 1899, 60: 1321-1334. Multiple benign sarcoid of the skin.
    Journal of Cutaneous and Genitourinary Diseases, Chicago, 1899, 17: 543-550. Weitere Beobachtungen über das multiple benigne Sarkoid der Haut. Mit 1 Tafel.
    Festschrift zu Ehren von Moriz Kaposi. Wien und Leipzig, 1900. 16 pages.
  • E. Kuznitsky, A. Bittorf:
    Boecksches Sarkoid mit Beteiligung innerer Organe.
    Münchener medizinische Wochenschrift, 1915, 62: 1349-1353.
  • J. Schaumann:
    Étude sur le lupus pernio et ses rapports avec les sarcoides et la tuberculose.
    Annales de dermatologie et de syphilographie, Paris, 1916-1917; 6: 357-373. Recherches sur le lupus pernio et ses relations avec les sarcoides cutnées.
    Nordiskt medicinskt Arkiv, Stockholm, 1917; afd. II, nr. 17: 1-81. Sur une forme érythrodermique de lymphogranulome bénin.
    Annales de Dermatologie et de Syphiligraphie, Paris, 1920; 1: 561-574. Le lupus pernio et les sarcoides au point de vue étiologique.
    Acta Dermato-Venereologica, Stockholm, 1923: 679-696. Sur le lupus pernio.
    Mémoire présenté en Novembre 1914 à la Societé française de Dermatologie et de Syphiligraphie pour le Prix Zambaco. Stockholm, P. A. Norstedt & Söner, 1934: 1-34. Lymphogranuloma benigna in the light of prolonged clinical observations and autopsy findings.
    British Journal of Dermatology, Oxford, 1936; 48: 399.
  • M. A. Kveim:
    En ny og spesifikk kutan-reaksjon ved Boecks sarcoid. En foreløpig meddelelse.
    Nordisk Medicin, Stockholm, 1941, 9: 169-172. The Kveim test.
    Leitartikel, Lancet, London, 1962/I: 1117-1119:
  • N. C. G. Danbolt:
    Re-examination of Caesar Boecks first patient with ”multiple benign sarcoid of the skin”.
    Schweizerische medizinische Wochenschrift, Basel, 1947, 77: 1149-1150.

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