Gilchrist's disease

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A chronic progressive, granulomatous and systemic disease caused by the fungus Blastomyces dermatitidis. It occurs almost exclusively in North America

Description

A chronic progressive, granulomatous and suppurative systemic disease caused by the fungus Blastomyces dermatitidis. It occurs almost exclusively in North America and is is endemic to the southeastern and midwestern United States. The cutaneous lessions are characterized by papules or papulopustules which develop into crusted, warty eruptions, and oozing sinuses. Areas of the face, particularly the facial orifices, are common sites. When the infection is widespread the urogenital system – bladder, kidney, prostate, testes – may be affected. The respiratory tract is the usual portal of entry. Infection is often associated with outdoor activities like camping, logging, and hunting.

Blastomycosis was first described by the French botanist and biologist Philippe Edouard Léon Van Tieghem (1839-1914) in 1876.

We thank Sarah Meisner for information submitted.

Bibliography

  • T. C. Gilchrist:
    A case of blastomycetic dermatitis in man.
    The Johns Hopkins Hospital Reports, 1896, 1: 269-290.
  • T. C. Gilchrist:
    Protozoan dermatitidis.
    Journal of Cutaneous and Genito-Urinary Diseases, New-York, 1894, 12: 496.
  • T. C. Gilchrist and W. R. Stokes:
    The presence of an Oidium in the tissues of a case of pseudo-lupus vulgaris: preliminary report.
    Bulletin of the Johns Hopkins Hospital, Baltimore, 1896, 7: 129-137.
  • T. C. Gilchrist and W. R. Stokes:
    A case of pseudo-lupus vulgaris caused by Blastomyces.
    The Journal of Experimental Medicine, New York, 1898, 53-83.

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