- A dictionary of medical eponyms

Reynolds' syndrome (Telfer B. Reynolds)

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A syndrome of chronic liver disease characterized by the coexistence of progressive systemic sclerosis and primary biliary cirrhosis.

Description

A syndrome of chronic liver disease characterized by the coexistence of progressive systemic sclerosis and primary biliary cirrhosis. Other features include jaundice, elevated alkaline phosphatase activity, Raynaud's phenomenon, calcinosis cutis, telangiectasia, and pruritus. Raynaud's phenomenon is an early clinical symptom for the evolution of a Reynolds' syndrome.

Bibliography

  • T. B. Reynolds, E. K. Denison, H. D. Frank, F. L. Lieberman, R. L. Peters:
    Primary biliary cirrhosis with scleroderma, Raynaud's phenomenon and telangiectasia. New syndrome.
    American Journal of Medicine, New York, 1971, 50 (3): 302-312.
  • Volker Stadie, Johannes Wohlrab, Wolfgang Christian Marsch:
    The Reynolds' Syndrome - a Rare Combination of Two Autoimmune Diseases.
    Medizinische Klinik, M√ľnchen, 2002, 97 (1): 40-43.

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