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Lhermitte-McAlpine syndrome
Associated persons:
Jacques Jean Lhermitte
Archibald Douglas McAlpine
Description:
A combined pyramidal and extrapyramidal tract syndrome in middle-aged and elderly persons. It is characterised by Parkinsonian rigidity, slowness of movement, loss of associated movements, and a choreiform type of muscular activity of the face, larynx, and pharynx. Other features include mental deterioration with apathy, hallucinations, negativism, delirium, and confusion. It is arteriosclerotic in origin.
Bibliography:
- J. Lhermitte, D. McAlpine:
A clinical and pathological résumé of combined disease of the pyramidal and extrapyramidal systems, with special reference to a new syndrome.
Brain, Oxford, 1926, 49: 157-181.
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