Both sexes affected; onset insidious, usually, after 40 years of age. Unilateral weakness, dysphagia; visual impairment up to blindness; aphasia; alteration of consciousness up to dementia. Caused by viral infection (papovirus SV40; JC).
- K. Åström, E. L. Mancall, E. P. Richardson Jr:
Progressive multifocal leukoencephalopathy: A hitherto unrecognised complication of chronic lympahtic leukemia and Hodgkin's disease.
Brain, Oxford, 1958, 81: 93-111.
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