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Felty's syndrome

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Atypical form of rheumatoid arthritis with fever, splenomegaly and leukopenia and, in some cases, anaemia and thrombocytopenia. Other features can include anorexia, weight loss, recurrent infections, brown pigmentation of exposed skin surfaces, peripheral neuropathy, carpal tunnel syndrome, arteritis, general malaise, pain in the upper left quadrant of the abdomen, Raynaud's syndrome and scleritis. Occurs most often in patients with a sustained period of illness, more often in women than in men.

Still disease or syndrome, also called Still-Chauffard-Felty syndrome, is a juvenile form. See under Sir George Frederick Still, English paediatrician, 1868-1941.


  • A. R. Felty:
    Chronic arthritis in the adult, associated with splenomegaly and leucopenia. A report of 5 cases of an unusual clinical syndrome.
    Bulletin of the Johns Hopkins Hospital, Baltimore, 1924, 35: 16.

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