Still's disease or syndrome

Alternative eponyms

Related people

A rare chronic, inflammatory, systemic disease which may cause joint or connective tissue damage and visceral lesions throughout the body.

Description

A rare chronic, inflammatory, systemic disease which may cause joint or connective tissue damage and visceral lesions throughout the body. In very young children it is characterized by general illness, fever, and rashes, with comparatively mild joint involvement. In older children, the adult pattern of the illness is seen, with predominant joint involvement and little or no general illness.

Onset in childhood or early adolescence. Etiology unknown. Complete remission occurs in 75% of patients.

Adult onset Still's disease is described as polyarthritis associated with sudden onset of high spiking fever, sore throat, and an evanescent erythematous salmon-colored rash.

Chronic arthritis in childhood was first described by André Victor Cornil (1837-1898). Felty's disease is an adult form.

Bibliography

  • V. Cornil:
    Mémoire sur les coincidences pathologiques du rhumatisme articulaire chroniques.
    Comptes rendus des séances et mémoires de la Société de biologie, Paris, 1864-1865; 1 (2): 3-25.
  • A. Chauffard, F. Ramon:
    Des adénopathies dans le rhumatisme chronique infectieux.
    Revue de médecine, Paris, 1896; 16: 345.
  • G. F. Still:
    A special form of joint disease met with in children.
    Doctoral dissertation, Cambridge, 1896. On a form of chronic joint disease in children.
    Medico-Chirurgical Transactions, London, 1897; 80: 47-59.

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