- A dictionary of medical eponyms

Brooke's epithelioma

Alternative eponyms

  • Ancell’s syndrome
  • Ancell-Spiegler cylindroma
  • Brooke's disease
  • Brooke's tumour
  • Brooke-Fordyce disease
  • Brooke-Fordyce trichoepithelioma
  • Brooke-Spiegler phakomatosis
  • Brooke-Spiegler syndrome
  • Spiegler's syndrome
  • Spiegler’s tumour

Related people

A usually benign skin disease most commonly occurring on the face, around the eyelids and on the scalp.

Description

A usually benign skin disease most commonly occurring on the face, around the eyelids and on the scalp. The lesions form firm, flesh-coloured, translucent papules with slight surface telangiectasia; small lesions may coalesce to form a solid sheet tumor. They usually appear near puberty and become stationary after enlarging for several years. Regression and, rarely, malignant degeneration may occur. Etiology unknown. A familial disease transmitted as an autosomal dominant trait. The small scalp lesions have been called Ancell-Spiegler's tumours, the lesions affecting especially nasolabial area Brooke-Fordyce trichoepitheliomas.

Bibliography

  • H. Ancell:
    History of a remarkable case of tumours developed on the head and face.
    Medico-Chirurgical Transactions, London, 1842, 25: 227-247.
  • H. A. G. Brooke:
    Epithelioma adenoides cysticum.
    British Journal of Dermatology, Oxford, 1892, 4: 269-286.
  • J. A. Fordyce:
    Multiple benign cystic epithelioma of the skin.
    Journal of Cutaneous and Genitourinary Diseases, Chicago, 1892, 10: 459-473.
  • E. Spiegler:
    Über Endotheliome der Haut.
    Archiv für Dermatologie und Syphilis, Berlin, 1899, 50: 163-176.

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