- A dictionary of medical eponyms

Fox-Fordyce disease

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A rare, chronic disease similar to prickly heat in which itchy follicular papules are present in the axillae, areola of the breast, umbilicus, pubic area, and labia majora. Pruritus is intense and sometimes almost intolerable. Almost exclusively in women, usually manifests in puberty.

Not to be confused with Fordyce’s disease, which consists of hypertrophic sebaceous glands or mucous membranes.


  • G. H. Fox, J. A. Fordyce:
    Two cases of a rare papular disease affecting the axillary region.
    Journal of Cutaneous and Genitourinary Diseases, Chicago, 1902, 20: 1-5.

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