- A dictionary of medical eponyms

Darier-White syndrome

Related people

A skin disease with onset in childhood, usually around the age of ten years, rarely in infants. Very long list of symptoms include many confluent flesh-coloured keratotic papules forming greasy and vegetating crusted areas, covering the seborrheic areas of the body: the chest, ears, nasolabial folds, scalp, neck, back, abdomen, and groin. On removing the lesion, a porelike opening is revealed. Eventually, the lesions coalesce into large, sometimes thick plaques to form hypertrophic, foul-smelling masses. Both sexes affected. Aetiology unknown. The condition tends to be aggravated by sunlight. Autosomal dominant inheritance.

Some authors consider this as a variant of Hopf’s syndrome (acrokeratosis verruciformis). See under Gustav Hopf, German dermatologist, 1900-1979.


  • H. C. Lutz:
    De l’hypertrophie générale du système sebacé.
    Paris, Thèse No. 65, 1860.
  • J. C. White:
    A case of keratosis (ichtyosis) follicularis.
    Journal of Cutaneous and Genitourinary Diseases, Chicago, 1889, 7: 201-209.
  • F. J. Darier:
    De la psorospermose folliculaire végétante. Étude anatomo-pathologique d'une affection cutanée non décrite ou comprise dans le groupe des acnés sebacées, cornées, hypertrophiantes, des kératoses (ichtyoses) folliculaires, etc.
    Annales de dermatologie et de syphilographie, Paris, 1889, 10: 597-612.
  • F. J. Darier et Thibault:
    De la psorospermose folliculaire végétante- Étude anatomo-pathologique d’une affection cutanée non décrite ou comprise dans le groupe des acnés sébacées, cornées hypertrophiantes, des kératoses (ichtyoses) folliculaires.
    Thèse de Paris. 1889.

What is an eponym?

An eponym is a word derived from the name of a person, whether real or fictional. A medical eponym is thus any word related to medicine, whose name is derived from a person.

What is Whonamedit?

Whonamedit.com is a biographical dictionary of medical eponyms. It is our ambition to present a complete survey of all medical phenomena named for a person, with a biography of that person.


Whonamedit? does not give medical advice.
This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor.