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Leyden-Möbius syndrome

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A musculare dystrophy involving first either the pelvic (Leyden-Möbius) or, less commonly, the shoulder girdle (Erb’s type). Occasionally there is pseudohypertrophy with wasting of the calves, and facial involvement. Onset is usually in childhood at the age of 10 to 12 years, but it may appear in adult or middle-age persons. Occurs in both sexes. The disorder is transmitted as an autosomal recessive trait, but sporadic cases also occur.


  • E. V. von Leyden:
    Klinik der Rückenmarks-Krankheiten.
    2 volumes. Berlin, Hirschwald, 1876. Volume 2, page 527.

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