Crabtree's effect
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A metabolic effect typical of tumour tissue: inhibition of cellular respiration by high concentration of glucose.
Bibliography
- H. G. Crabtree:
Observations on the carbohydrate metabolism of tumors.
The Biochemical Journal, London, 1929, 23: 536, 545.
Crabtree noted that "the glycolytic activity of tumour cells exerts a checking effect on their respiration."
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