- A dictionary of medical eponyms

Castleman's tumour

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Unusual mediastinal lymph node hyperplasia resembling thymoma. It is probably a benign hyalinating lymphoma originating from plasma cells. The characteristic histologic features include an onion skin arrangement of the lymphocytes in nodules and an unusual vasculature with marked capillary proliferation. The multicentric variant with general symptoms is prognostically more serious. Usually solitary and on resection may not recur.


  • B. Castleman, L. Inversion, V. Pardo Menendez:
    Localized mediastinal lymphnode hyperplasia resembling thymoma.
    Cancer, Philadelphia, 1956, 9: 822-830.

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