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Shulman's syndrome

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A syndrome characterised by acute onset of erythema and later induration of the connective tissues of the extremities, but sparing the hands, usually appearing following exertion. Laboratory findings are eosinophilia, hypergammaglobulinaemia and a raised erythrocyte rate. Spontaneous remissions can occur. Occurs mainly in middle-aged men.


  • L. E. Shulman:
    Diffuse fasciitis with hyperglobulinemia and eosinophilia: A new syndrome?
    Journal of Rheumatology, Toronto, Supplement, 1974, 1: 46.
  • S. H. Pincus:
    Cutaneous eosinophilic diseases.
    In: T. B. Fitzpatrick, A. Z. Eisen, K. Wolff, I. M. Freedberg, K. F. Austen, editors: Dermatology in General Medicine. 3rd edition; New York, McGraw-Hill, 1987, pp. 1336-1344.

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