- A dictionary of medical eponyms

Freiberg-Köhler syndrome

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Osteochondrosis of a metatarsal head, usually the second (more rarely 3.rd or 4th.) metatarsal bone of the foot, presenting the picture of subchondral cancellous bone necrosis. Characterized by localized pain and swelling over the metatarsal head, overlying skin red,. and limitation of movement in an adolescent. X-rays show the head to be crushed and fragmented. Occurs most often in girls aged 10 to 18 years.

We thank Amy Tsang for correcting an error.


  • A. H. Freiberg:
    Infarction of the second metatarsal bone. S. G. O., 1914, 19: 191-193. The so-called infarction of the second metatarsal bone.
    Journal of Bone and Joint Surgery, Boston, 1926, 8: 257-261.
  • A. Köhler:
    Ueber eine häufige, bisher anscheinend unbekannte Erkrankung einzelner kindlicher Knochen.
    Münchener medizinische Wochenschrift, 1908, 55: 1923-1925.
  • Eine typische Erkrankung des 2. Metatarsophalangealgelenkes.
    Münchener medizinische Wochenschrift, 1920, 67: 1289-1290.
    English translation in The American Journal of Roentgenology, 1923, 10: 705-710.

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