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Lieberkühn's glands

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Simple tubular glands which open into the intestine, present in the mucous membrane of the small and large intestines.

Lieberkühn described the glands in 1745, but they were first discovered by Marcello Malpighi (1628-1698) in 1688 and were described anew by Johann Konrad Brunner (1653-1727) in 1715 and by Dom Mar. Gusman Galeazzi (Galeati) (1686-1775) in 1731.


  • M. Malpighi:
    De structura glandularum conglobatarum consimiliumque partium epistolae.
    London, 1689; Leyden, 1690.
    Since Malpighi discovered the intestinal glands in 1688, we assume this is the reference work.
  • J. K. Brunner:
    Glandula duodeni, seu pancreas secundarium detectum.
    Frankfurt and Heidelberg, 1715.
  • J. N. Lieberkühn:
    Dissertatio de fabrica et actione villorum intestinorum tenuium hominis.
    Lugduni Batavorum (Leiden), C. & G. J. Wishof, 1745.

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