- A dictionary of medical eponyms

Rotor's syndrome

Related people

A rare idiopathic form of hyperbilirubinaemia affecting both sexes, with onset shortly after birth or in childhood. It is characterised by nonhaemolytic jaundice, attacks of intermittent epigastric discomfort and occasionally abdominal pain, and fever. Pathological findings include low-grade pigment deposition, dissociation of liver cells, occasional necrotic foci, and fibrin precipitation. Aetiology unknown. Possibly, autosomal recessive inheritance. It is due to a defect in the excretion of unconjugated bilirubin into the biliary craniculi with the bilirubin being absorbed into the blood and excreted in the urine. Primarily reported in patients from the Philippines.

Rotor’s syndrome is similar to the Dubin-Johnson syndrome, except that the gall bladder is usually visualised on an oral cholecystogram and there is no secondary appearance of the dye during the performance of bromsulphaphtalien. May be the same condition as hepatic storage disease reported in Japan and France.


  • A. B. Rotor, L. Manahan, Angel Florentin:
    Familial non-hemolytic jaundice with direct van den Bergh reaction.
    Acta medica Philippina, Manila, 1948, 5: 37-49.

What is an eponym?

An eponym is a word derived from the name of a person, whether real or fictional. A medical eponym is thus any word related to medicine, whose name is derived from a person.

What is Whonamedit?

Whonamedit.com is a biographical dictionary of medical eponyms. It is our ambition to present a complete survey of all medical phenomena named for a person, with a biography of that person.


Whonamedit? does not give medical advice.
This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor.