- A dictionary of medical eponyms

Silfverskiöld's syndrome

Related people

An unusual form of osteochondrodystrophy with skeletal defects, mainlsiy slight vertebral changes with shortened or curved long bones. In 1925 and 1926 Silfverskiöld described a total of 5 patients with 4 different skeletal dysplasias. As the disease pictures vary greatly, it is imposssible to give any usable definition. However, Silfverskiöld deserves credit for distinguishing a series of skeletal dyslpasias from achondroplasia.

Silfverskiöld’s patient was an eleven-year old boy in whom the symptoms included disproportionate dwarfism with short legs, large head, and flattened nose, broad chest, large head, and flattened nose, broad chest, and large trochanters. Bearing and gait resembled that seen in bilateral luxation of the hip joint with marked lumbar lordosis and accentuated inclination of the pelvis. Lordosis due to flexion contractures of the hips. The upper arms were shorter and forearms were longer than normal. Other features include genu valgum, coxa vara, loose joints, and powerful musculature. The aetiology in unknown

It is possibly a variant of Morquio’s syndrome. Term is obsolete in modern nomenclature.

Hans Fredrik Helweg-Larsen (1917-1969) and Mørch later reported the syndrome in a family. The skeletal changes are transmitted as a simple dominant character.


  • N. Silfverskiöld:
    A «forme fruste» of chondrodystrophia with changes simulating several of the known «local malacias».
    Acta radiologica, Stockholm 1925, 4: 44-57. Sur la question de la achondroplasie et de sa forme périphérique.
    Acta radiologica, Stockholm, 1926, 5: 233.
  • Z. Grudzinski:
    Über eine neue mit Achondroplasie (Chondrodystrophie) verwandte Krankheitsform. (Osteochondropathia multiplex Grudzinski, Achondroplasia atypica Silfverskiöld, Dystrophie spongieuse epiphysaire systematisée Ghimus).
    Fortschritte auf dem Gebiete der Röntgenstrahlen, Hamburg, 1928, 38: 873-882.

What is an eponym?

An eponym is a word derived from the name of a person, whether real or fictional. A medical eponym is thus any word related to medicine, whose name is derived from a person.

What is Whonamedit?

Whonamedit.com is a biographical dictionary of medical eponyms. It is our ambition to present a complete survey of all medical phenomena named for a person, with a biography of that person.


Whonamedit? does not give medical advice.
This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor.