- A dictionary of medical eponyms

Westphal-Leyden ataxia

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Acute ataxia with onset in childhood. It presents with vomiting, vertigo, proximal muscle rigidity, and coma. Later symptoms include slow scanning speech; ataxia with convulsive seizures and slow jerky movements of the extremities, mental disorders, faulty memory, and dementia. Sensitivity and motor strength apparently unaffected. Both sexes affected. Death within 10 years. Final stage indistinguishable from Huntington's chorea. Undetermined aetiology. Possibly autosomal dominant inheritance.


  • C. Westphal:
    Eigentümliche mit Einschlafen verbundene Anfälle.
    Archiv für Psychiatrie und Nervenkrankheiten, Berlin, 1877, 7: 631-635.
  • E. Leyden:
    Ueber acute Ataxie.
    Zeitschrift für klinische Medicin, Berlin, 1891, 18: 576.
  • F. K. Gökay, K. Tükel:
    Kardeste Ailevi kortiko-striyato-serebellar sendrom vakalari.
    Turk Tip Cemiyeti Mecmuasi Yil, 1947, 13: 7.
We thank André Trombeta for information submitted.

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