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Hallopeau's syndrome I

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A chronic atrophic skin disease prevalent in females (ca 6:1), characterized by irregular, firm, mother-of.-pearl or ivory-coloured flat-topped papules with erythematous halos surrounding the white spots. The papules are round or oval; they have shining smooth surfaces and contain dark, comeolike plugs or minute depressions caused by former plugs. In advanced stages, coalescing papules may form large lesions and atrophy may occur. Bullae, haemorrhage, hyperpigmentation, and exfoliation may be present. Onset at any age, but usually around menopause (average age in females 50, males 43).

See also Neumann's disease, under Isidor Neumann Edler von Heilwart, Austrian dermatologist, 1832-1906.


  • I. Neumann:
    Über Pemphigus vegetans (framboesioides).
    Wiener medizinische Blätter, 1886, 9: 46.
  • F. H. Hallopeau:
    Du lichen plan, et particulièrement de sa forme atrophique.
    Union médicale, Paris, 1887, 43: 729-733.
  • Lichen plan scléreux.
    Annales de dermatologie et de syphilographie, Paris, 1889, 20: 447-449.
  • F. H. Hallopeau:
    Nouvelle étude sur une forme pustuleuse et bulleuse de la maladie de Neumann, dite pemphigus végétans.
    Annales de dermatologie et syphiligraphie, Paris, 1898, 9: 969.
  • L. von Zumbusch:
    Über Lichen albus, eine bisher unbeschriebene Erkrankung.
    Archiv für Dermatologie und Syphilis, Berlin, 1906, 82: 339-350.
  • J. Csillag:
    Dermatitis lichenoides chronica atrophicans (Lichen albus v. Zambusch).
    In: Albert Neisser and Eduard Jacobi, editors: Ikonographia dermatologica. Berlin, 1909, pp 147-151.

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