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Ascher's syndrome

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A combination of blepharochalasis, doublelip and, nontoxic goiter. Onset at young age with transient, recurrent edemas of angioneurotic type in both eyelids (usually, only the superiors; occasionally, also the inferiors). Then with the progress of the disease, prolapse of the orbital fat and lacrimal glands and blepharoptosis. Unknown etiology; genetic cause has been suggested.


  • E. Fuchs:
    Ueber Blepharochalasis (Erschlaffung der Lidhaut).
    Wiener klinische Wochenschrift, 1896, 9: 109.
  • W. B. Laffer:
    Blepharochalasis. Report of a case of this trophoneurosis, involving also the upper lip.
    Cleveland Medical Journal, 1909, 8: 131-135.
  • K. W. Ascher:
    Blepharochalasis mit Struma und Doppellippe.
    Klinische Monatsblätter für Augenheilkunde, Stuttgart, 1920, 65: 86-97.

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