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Fuchs' heterochromic cyclitis

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A congenital disorder of the eye, with heterochromia (a difference in colour between the irises or differences of colour in the same iris), uveitis of the lighter coloured eye, iridocyclitis (inflammation of the iris and ciliary body), keratitic precipitates and often catarct. Unilateral heterochromia, cyclitis, and secondary cataracts characterize this syndrome. Onset in the third to fourth decades of life. Insidious onset; patient in most of the cases is unaware of condition until opafication of vitreous reduces vision.

First described in 1904 by the French ophthalmologist Georges Weill (1866-1952). A larger survey by Fuchs 1906. Previously the association of cyclitic appearances and iris heterochromia had been noticed by Sir William Lawrence (1783-1867), Sir Jonathan Hutchinson (1828-1913), Bistis, Robert Marcus Gunn (1850-1909), and Malgrat.


  • E. Fuchs:
    Über Komplikationen der Heterochromie.
    Zeitschrift für Augenheilkunde, Basel, 1906, 15: 191-212.

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