- A dictionary of medical eponyms

Döhle-Heller syndrome

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A common manifestation of tertiary syphilis. Aortitis secondary to syphilis, sometimes complicated by aortic valve insufficiency, coronary stenosis, and aortic aneurysm. Both sexes affected but more prevalent in males; average age at onset was 35 to 55 years (today higher, 60-65 years). In untreated cases of syphilis, present in 75 % of cases. Clinically manifested in only 10 % of affected individuels.


  • G. Döhle:
    Ein Fall von eigentümlicher Aortenerkrankung bei einem Syphilitischen.
    Kiel, Lipsius und Tischer, 1885.
  • A. L. Heller:
    Ueber die syphilitische Aortitis und ihre Bedeutung für die Entstehung von Aneurysmen.
    Verhandlungen der deutschen pathologischen Gesellschaft, Stuttgart, 1900, page 346.

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