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Lightwood-Albright syndrome

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This eponym comprises a mild and transient form of renal tubular acidosis which appear in the 1st year of life. Lightwood-Albright form consists of hyperchloremic acidosis and nephrocalcinosis. The symptoms include anorexia, failure to gain weight, dehydration, severe constipation, hypotonia and vomiting. In older children they may also include rickets, bone deformities, pathological fractures, and growth retardation.


  • R. Lightwood:
    Calcium infarction of the kidneys in infants. Communication, Proc Br Paediatr Soc. Archives of Disease in Childhood, London, 1935, 10: 205-206.
  • F. Albright, W. V. Consolazio, F. S. Coombs, J. H. Talbot; H. W. Sulkowitch:
    Metabolic studies and therapy in a case of nephrocalcinosis with rickets and dwarfism.
    Bulletin of the Johns Hopkins Hospital, Baltimore, 1940, 66: 7-33.
  • A. Butler, et al:
    Dehydration and acidosis with calcification of renal tubules.
    Journal of Pediatrics, St. Louis, 1936, 8: 489-499.

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