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Balfour's disease
Also known as:
Aran’s cancer
Nägeli’s disease
Associated persons:
François-Amilcar Aran
John Hutton Balfour
Otto Nägeli
Description:
A disturbance characterized by multiple tumorous masses formed by the bony infiltrates in myelogenous leukemia. May be present in any portion of the skeleton, but are found most frequently in the skull. They are usually greenish, due to the presence of the green pigment myeloperoxidase. When present, the color tends to fade after exposure to air.
The disturbance was described as early as in 1811 by Allan Burns (1781-1813).
Bibliography:
- A. Burns:
Observations on the surgical anatomy of the head and neck. Glasgow, 1811.
- J. H. Balfour:
Case of peculiar disease of the Skull and Dura mater.
Edinburgh Medical and Surgical Journal, 1835, 43: 319-325.
- F. A. Aran:
Notes sur une forme particulière et encore peu connue de cancer de la dure mère et des os du crâne (cancer vert).
Archives générales de médecine, Paris, 1854; 5. sér., 4: 385.
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