- A dictionary of medical eponyms

Seitelberger's disease II

Related people

A rare familial form of demyalinating disease with early onset and absence of stainable myelin. The affected child is normal at birth and development is normal up to second year of life. Then the disturbance develops with difficulty in standing and walking; progressive deterioration of neurological function and speech; incontinence during sleep; nystagmus, strabismus, blindness, seizures, tendon hyporeflexia or areflexia; or initially pathologic reflexes, flexion, and deformation. Both sexes affected.

It is a variant of the Pelizaeus-Merzbacher syndrome and has some resemblance with the Hallervorden-Spatz disease.

See also:
Pelizaeus-Merzbacher syndrome (sudanophilic leukodystrophy) under Friedrich Peliz├Žus, German neurologist, 1850-1917.

Hallervorden-Spatz disease (progressive pallidal degeneration syndrome) under Julius Hallervorden, German neurologist, 1882-1965.


  • F. Seitelberger:
    e unbekannte Form von infantiler Lipoidspeicherkrankheit des Gehirns.
    Proceedings of the First International Congress of Neuropathology (Rome, September 8-13, 1952). Volume 3. Rosenberg and Sellier, Turin. 1952.
  • F. Seitelberger:
    Die Pelizaeus-Merzbachersche Krankheit. Klinisch-anatomische Untersuchung zum problem ihrer Stellung unter den diffusen Sklerosen.
    Wien Zschr Nervenh, 1954, 9: 228-289.

What is an eponym?

An eponym is a word derived from the name of a person, whether real or fictional. A medical eponym is thus any word related to medicine, whose name is derived from a person.

What is Whonamedit?

Whonamedit.com is a biographical dictionary of medical eponyms. It is our ambition to present a complete survey of all medical phenomena named for a person, with a biography of that person.


Whonamedit? does not give medical advice.
This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor.