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Ehrlich's finger test
Associated persons:
Paul Ehrlich
Description:
In vivo test for demonstrating a haemolysis caused by biphasic cold haemolysins (Donath-Landsteiner antibodies). The patient's venously clogged finger is first held in ice water for 10 minutes and then in water with a temperature of 40° C. In positive cases there is a haemolysis in the serum from the capillary blood which is taken from the tip of the finger. An erythrocyt phagocytosis is often demonstrable in the blood smear.
Bibliography:
- P. Ehrlich:
Über paroxysmale Hämoglobinurie.
Deutsche medicinische Wochenschrift, Berlin, 1881, 7: 224-235.
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