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Schaumann's bodies
Associated persons:
Jörgen Nilsen Schaumann
Description:
Inclusion bodies composed of calcium and proteins in the giant cells (Langhans’ giant cells) seen in granulomatous conditions such as sarcoidosis and berylliosis. They are rounded, with a diameter of 8-300 µ, made up of concentrically layered lamella. They are easily recognized in infrared light.
These bodies were first described by the German physician Oscar von Schüppel (1837-1881) in 1871, and by Max Askanazy (1865-1940) in 1921 as Kalkdrusen.
Bibliography:
- O. Schüppel:
Untersuchungen über Lymphdrüsentuberkulose. Tübingen, 1871.
- M. Askanazy:
Über lupöse Tuberkulose des Blutbildungsapparates und tuberkulöse Splenomegalie.
Beiträge zur pathologischen Anatomie und zur allgemeinen Pathologie, 1921, 69: 563-582.
- J. Schaumann:
Recherches sur le lupus pernio et sur les relations avec les sarcoides cutanées et sous-cutanées.
Annales de dermatologie et de syphilographie, Paris, 1917, 5: 357-373.
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