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Romano-Ward syndrome

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Prolongation of Q-T interval on the electrocardiogram, usually in association with syncope, ventricular tachyarrythmia, and sudden death. Sudden death can occur in childhood, and death during the induration of an anaesthethic can occur at any age. The disorder may be sporadic or transmitted as a genetic trait. Symptoms and signs include all those present in Jervell and Lange-Nielsen syndrome. When associated with deaf mutism and transmitted as an autosomal recessive trait, the prolonged QT interval syndrome is known as the Jervell and Lange-Nielsen syndrome, and when transmitted as an autosomal dominant trait, without deafness, it is referred to as the Romano-Ward syndrome.


  • C. Romano, G. Gemme, R. Pongiglione:
    Aritmie cardiache rare dell’ etá pediatrica. II. Accessi sincopali per fibrillazione ventricolare parossistica.
    Clinica pediatrica, Bologna, 1963, 45: 656-683.
  • O. C. Ward:
    A new familial cardiac syndrome in children.
    Journal of the Irish Medical Association, 1964, 54: 103-107.
  • John B. Barlow, C. K. Bosman, J. W. C. Cochrane:
    Congenital cardiac arrythmia.
    The Lancet, London, 1964, II: 531.

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