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Arthus's phenomenom
Also known as:
Arthus's reaction
Associated persons:
Nicolas Maurice Arthus
Description:
A severe local inflammatory reaction with localized destruction of tissue, resulting from antigen-antibody (IgE) combination; occurs at the site of repeated injection of a nonirritating antigen (such as egg albumin) to which the animal already has precipitating antibody. It is considered an immediate hypersensitivity reaction.
Bibliography:
- N. M. Arthus:
Injections répétées de serum du cheval zhez le lapin.
Comptes rendus des séances de la Société de biologie, Paris, 1903; 55: 817-820.
Abbreviated English translation in Bibel, Milestones of Immunology, 1988.
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