Arthus's phenomenom

Alternative eponyms

Related people

A severe local inflammatory reaction with localized destruction of tissue, resulting from antigen-antibody (IgE) combination.

Description

A severe local inflammatory reaction with localized destruction of tissue, resulting from antigen-antibody (IgE) combination; occurs at the site of repeated injection of a nonirritating antigen (such as egg albumin) to which the animal already has precipitating antibody. It is considered an immediate hypersensitivity reaction.

Bibliography

  • N. M. Arthus:
    Injections répétées de serum du cheval zhez le lapin.
    Comptes rendus des séances de la Société de biologie, Paris, 1903; 55: 817-820.
    Abbreviated English translation in Bibel, Milestones of Immunology, 1988.

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