- A dictionary of medical eponyms

Hajdu-Cheney disease

Alternative eponyms

  • Cheney’s dentoarthro-osteo dysplasia
  • Cheney-Hajdu syndrome
  • Giaccai’s syndrome 1
  • Hajdu's syndrome

Synonyms

Acro-osteolysis syndrome, acro-osteolysis type Hajdu-Cheney, acro-osteolysis-osteoporosis-skull changes, arthrodento-osteodysplasia, cranio-skeletal dysplasia, inheritable idiopathic osteolysis type VI.

Related people

An autosomal dominant form of acro-osteolysis.

Description

A hereditary condition characterized by stunted stature, wormian bones, slowly progressive skeletal dysplasia which affects the skull, spine, and long bones, loss of the terminal phalanges of the hands and feet sometimes giving the appearance of clubbing with osteoporosis. Resorption of the alveolar process and early loss of teeth are the principal dental features. Joint laxity is a frequent feature.
Bone fractures from minor traumas. Both sexes affected. Aetiology unknown. Inheritance is autosomal dominant. Sporadic cases are believed to represent a fresh gene mutation.

An early description of single cases was made in 1948 by Hajdu and Ralph Kauntze [London]. In 1965 Cheney recognized the genetical character of the disturbance.

Bibliography

  • N. Hajdu, R. Kauntze:
    Cranio-skeletal dysplasia.
    British Journal of Radiology, London, 1948, 21: 42-48.
  • W. D. Cheney:
    Acro-osteolysis. American Journal of Roentgenology, 1965, 94: 595-607.
  • I. Marik, M.Kuklik, D. Zemkowa, and K. Kozlowski:
    Hajdu-Cheney syndrome: Report of a family and a short literature review.
    Australasian Radiology, December 2006, 50 (6): 534-538.

What is an eponym?

An eponym is a word derived from the name of a person, whether real or fictional. A medical eponym is thus any word related to medicine, whose name is derived from a person.

What is Whonamedit?

Whonamedit.com is a biographical dictionary of medical eponyms. It is our ambition to present a complete survey of all medical phenomena named for a person, with a biography of that person.

Disclaimer:

Whonamedit? does not give medical advice.
This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor.