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Bowen's disease
Also known as:
Bowen's dermatosis
Bowen's epithelioma
Bowen's precancerous dermatosis
Bowen-Darier disease
Synonyms:
Dermatosis precancerosa, precancerous dermatitis, squamous cell carcinoma in situ.
Associated persons:
John Templeton Bowen
Ferdinand-Jean Darier
Louis Auguste Queyrat
Description:
Intraepidermal epithelioma (carcinoma in situ) with invasive power. Sharply circumscribed, often solitary inflammated reddish nodules with psoriasis-shaped, slightly raised, scaly or crusted plaque. Bowen disease may occur anywhere on the skin surface. Also commonly seen on the floor of the mouth, tongue, lips, and buccal mucosa, Today, Bowen's disease occurs most often in the sun-exposed areas of the skin in white males over 50. The corresponding lesion on the glans penis is termed erythroplasia of Queyrat.
Bibliography:
- J. T. Bowen:
Precancerous dermatoses: A study of two cases of chronic atypical proliferation.
The Journal of Cutaneous Diseases Including Syphilis, New York, 1912, 30: 241-255.
- J. T. Bowen:
Precancerous dermatoses: a sixth case of a type recently described.
The Journal of Cutaneous Diseases Including Syphilis, New York, 1915, 33: 787-801.
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