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Cantrell's sequence

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A congenital sequence of thoraco-abdominal malformations combining midline supraumbilical abdominal defects, defects of the lower sternum, deficiency of the diaphragmatic pericardium, deficiency of the anterior diaphragm, and cardiac defects. 2/3 of the patients have muscular diverticulum of the apical portion of left ventricle. The syndrome affects both males and females and is apparent at birth or shortly after.


  • J. R. Cantrell, J. A. Haller, M. M. Ravitch:
    A syndrome of congenital defects involving the abdominal wall, sternum, diaphragm, pericardium, and heart.
    Surgery, Gynecology and Obstetrics, Chicago, 1958, 107: 602-604.

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