- A dictionary of medical eponyms

Grawitz' tumour

Alternative eponyms

  • Grawitz' renal tumour
  • Grawitz' syndrome

Synonyms

Adenocarcinoma of kidney, hypernephroid tumour, clear cell carcinoma, hypernephroma, kidney adenocarcinoma, renal adenocarcinoma, renal cell carcinoma, strumasuprarenalis cystica haemorrhagica.

Related people

A malignant tumour of the kidney.

Description

Hypernephroma - renal cell carcinoma. A malignant tumour of the kidney. A typical lesion is a yellow or orange mass about 5 to 15 cm in diameter, with irregular cystic and hemorrhagic areas. Most tumours are composed of polygonal clear cells in varying arrangements – tubules or papillary formations – with a high concentration of lipids. Symptoms dull pain in lumbar region, and later anorexia, asthenia, nausea, weight loss, haematuria, and hyperthermia. Occasionally, colic. Both sexes affected; most commonly occurring on the fifth or sixth decade of life. In 40 % of cases asymptomatic. Aetiology unknown.

Bibliography

  • P. A. Grawitz:
    Die sogenannten Lipome der Niere.
    [Virchows] Archiv für pathologische Anatomie und Physiologie, und für klinische Medicin, Berlin, July 1883; 93 (1): 39-63.
  • P. A. Grawitz:
    Die Entstehung von Nierentumoren aus Nebennierengewebe.
    Verhandlungen der Deutschen Gesellschaft für Chirurgie, Berlin, 1884, 13 (2): 28-38.

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