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Kérandel's sign

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Delayed sensation to pain. Deep hyperaesthesia accompanied by pain, often delayed, after slight blow upon a bony projection of the body. It is a sign of beginning trypanosomiasis, or sleeping sickness. Described by Kérandel in 1908.

Kérandel's sign and Kerandel's symptom/key are two distinct symptoms of African human trypanosomiasis.

We thank Joseph Constantin, France, for information submitted.


  • J. P. Nozais:
    Mais ou est donc passée la "cle de Kérandel?
    [Where on earth has Kerandel's key gone?]
    Bulletin de la Société de pathologie exotique et de ses filiales, 1988, 81 (3 Pt 2): 477-479.

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