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Minot-Murphy diet
Associated persons:
George Richards Minot
William Parry Murphy
Description:
Diet for pernicious anaemia containing large quantities of raw liver. This treatment ranks as one of the greatest advances in therapy.
Bibliography:
- Georg Eduard Rindfleisch (1836-1908):
Ueber den Fehler der Blutkörperchenbildung bei der perniciösen Anämie.
[Virchows] Archiv für pathologische Anatomie und Physiologie und für klinische Medicin, Berlin, 1890, 121: 176-181.
Rindfleisch made the first clear statement of the bone marrow changes in pernicious anaemia.
- Frieda Saur Robscheit-Robbins (1893-1973) and George Hoyt Whipple (1878-1976):
Blood regeneration in severe anaemia. Favourable influence of liver, heart and skeletal muscle in diet.
American Journal of Physiology, 1925, 72: 408-418.
These workers showed the beneficial effect of raw beef liver upon blood regeneration in anaemia. Their work paved the way for the liver diet treatment of Minot and Murphy.
- George Richards Minot & William Parry Murphy:
Treatment of pernicious anemia by a special diet.
Journal of the American Medical Association, 1926, 87: 470-476.
- G. R. Minot:
The Development of Liver Therapy in Pernicious Anemia: A Nobel Lecture.
The Lancet, London, 1935, 1: 361-364.
- George R. Minot and William P. Murphy:
Treatment of pernicious anemia by a special diet. Blood, 1948, 3 (1).: 8-21.
We thank Rudolf Kleinert, Bad Reichenhall, Germany, for information submitted.
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