- A dictionary of medical eponyms

Rabl configuration

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A configuration in which the chromosome configuration of anaphase (centromeres pointing towards poles, telomeres dragging behind) is "frozen" throughout the next cell cycle.

Description

A configuration in which the chromosome configuration of anaphase (centromeres pointing towards poles, telomeres dragging behind) is "frozen" throughout the next cell cycle. The presence of the Rabl organization is known to vary greatly between species and among tissues or developmental stages of an organism. Some cells lose the Rabl organization soon after entering interphase, whereas others retain the organization through to the next mitosis.

Bibliography

    Definition by Pete Carlton at http://www.ocf.berkeley.edu/~pcarlton/meio.html, and:
  • Carrie R. Cowan, Peter M. Carlton, and W. Zacheus Cande:
    The Polar Arrangement of Telomeres in Interphase and Meiosis. Rabl Organization and the Bouquet. Plant Physiology, February 2001, 125: 532-538.

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