- A dictionary of medical eponyms

Van Slyke's test I

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Test for amide nitrogen. Manometric method for measuring blood gases. Nitrous acid acting on amide nitrogen sets free nitrogen gas, which is collected and its volume determined. Van Slyke's techniques for measuring blood gases led to better understanding of respiratory physiology.


  • Donald D. Van Slyke and Glenn E. Cullen:
    Studies of acidosis. The bicarbonate concentration of the blood plasma; its significance, and its determination as a measure of acidosis.
    The Journal of Biological Chemistry, 1917, 30 (2): 289.
    Preliminary report in Proceedings of the Society for Experimental Biology and Medicine, New York, 1915
  • Donald D. Van Slyke and W. C. Stadie:
    The Determination of the Gases in the Blood.
    The Journal of Biological Chemistry, Baltimore, 1921, 49: 1.
  • Donald D. Van Slyke:
    An apparatus for determination of the gases in blood and other solutions.
    Proceedings of the National Academy of Sciences of the United States of America, Washington D.C., 1921, 7: 299.

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