Ghon's primary lesion

Alternative eponyms

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A small, sharply defined shadow in roentgenographic film of the lung, the primary lesion in pulmonary tuberculosis in children.

Description

A small, sharply defined shadow in roentgenographic film of the lung seen in certain cases of pulmonary tuberculosis in children. It is a calcification seen in pulmonary parenchyma and hilar nodes resulting from earlier infection with tuberculosis, and is usually the primary lesion of tuberculosis in children. The term "primary lesion" was introduced by E. Rach, who characterised it thus on an X-ray picture (in German): "Solitärer Schatten, abseits vom Hilus, mit Vorliebe nahe der Pleura inmitten hellen Lungengewebes gelegen.» The primary lesion in pulmonary tuberculosis in children. Gohn’s primary focus was first described by Joseph Marie Jules Parrot (1829-1883).

Bibliography

  • J. Parrot:
    Recherches sur les relations qui existent entre les lésions des poumons et celles des ganglions trachéo-bronchiques.
    Comptes rendus de la Société de biologie, Paris, 1876, sér 6, 3: 308-309.
  • A. Ghon:
    Der primäre Lungenherd bei der Tuberkulose der Kinder.
    Berlin & Wien, Urbach & Schwarzenberg, 1912.

  • E. Rach:
    Röntgendiagnostik der kindlichen Lungenerkrankungen.
    Ergebnisse der Inneren Medizin und Kinderheilkunde (Berlin), 1927, 32: 464-530.
  • E. Rach:
    Radiologisch-klinische Semiotik der kindlichen Lungenerkrankungen.
    Zeitschrift für Kinderheilkunde, Berlin, 1917, 15: 1-45.

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