- A dictionary of medical eponyms

Miescher's granuloma (Alfred Guido Miescher)

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An annular lesion with raised border seen on skin chronically exposed to the sun. Microscopically it shows phagocytosis of dermal elastic fibres by giant cells and histiocytes. It is a histopathologic hallmark of erythema nodosum.


  • G. Miescher:
    Zur Histologie des Erythema nodosum.
    Acta dermato-venereologica, Stockholm, 1947, 27: 447-468.
  • M. J. Nubé:
    Miescher's granuloma in erythema nodosum.
    Dermatologica, Basel, 1050, 101: 80-84.
  • G. Miescher:
    Zur Frage der Radiärknötchen beim Erythema nodosum.
    Archiv für Dermatologie und Syphilis, 1951, 193: 251-256.

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