- A dictionary of medical eponyms

Sabin-Feldman syndrome

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A syndrome of toxoplasmosis like symptoms and extensive destruction of brain tissue, hydrocephalus, diffuse cerebral calcification, chorioretinopathy, microcephaly, mental retardation, and degenerative changes of small retinal vessels. Onset in early infancy. The syndrome has been reported in inbred groups as a hereditary condition transmitted as an autosomal recessive trait.


  • A. B. Sabin, H. A. Feldman:
    Chorioretinopathy associated with other evidence of cerebral damage in childhood. A syndrome of unknown etiology separable from congenital toxoplasmosis.
    Journal of Pediatrics, St. Louis, 1949, 35: 296-309.
  • V. A. McKusick, M. Stauffer, D. L. Lnox, D. B. Clark:
    Chorioretinopathy with hereditary microcephaly.
    Archives of Ophthalmology, Chicago, 1966, 75: 587-600.

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