Sister Mary Joseph's nodule

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A nodule deep in the subcutis in the umbilical area, associated with metastasis from tumours.

Description

A hard mass or nodule which can be seen or felt deep in the subcutis in the umbilical area. Sometimes present when pelvic or gastrointestinal tumours have metastasized.

Bibliography

  • William J. Mayo:
    Metastasis in cancer.
    Proceedings of the Staff Meetings of the Mayo Clinic, 1928, 3: 327.

  • H. Bailey:
    Demonstration of physical signs in clinical surgery.
    11th edition, Baltimore, Williams & Wilkins, 1949, p 227.
  • J. D. Key, D. A. Shepard, Walters:
    Sister Mary Joseph’s nodule and its relationship to diagnosis of carcinoma of the umbilicus.
    Minnesota Medicine, St. Paul, Minnesota, 1976, 59 (8): 561-566.

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