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Sézary's cell
Also known as:
Pautrier's abscess
Lutzner's cells
Sézary-Lutzner cells
Associated persons:
Marvin A. Lutzner
Lucien-Marie Pautrier
Albert Sézary
Description:
An atypical T lymphocyte that contains vacuoles filled with mucopolysaccharide. It is a characteristic finding in cutaneous T-cell lymphoma and its variants and present in the peripheral blood of patients with Sézary syndrome. Clusters of these cells in the epidermis is called Pautrier's microabscess.
We thank Andre Trombeta for information submitted.
Bibliography:
- A. Sézary, Y. Bouvrain:
Erythrodérmie avec présence de cellules monstrueuses dans le derme et le sang circulant.
Bulletin de la Société francaise de dermatologie et de syphiligraphie, Paris, 1938; 45: 254-260.
- A. Sézary:
Pathogénie et sémiologie des mélanodernies du type addisonien.
La presse médicale, Paris, 1921: 281-283.
- M. A. Lutzner, H. W. Jordan:
The ultrastructure of an abnormal cell in Sézary syndrome.
Blood, June 1968, 31 (6): 719-726.
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