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Donath-Landsteiner syndrome


Associated persons:
Julius Donath
Karl Landsteiner

Description:
A very rare autoimmune haemolytic disorder. Haemoglobinuria characterized by the sudden passage of dark brownish to black urine following exposure to cold, often associated with leg pain, abdominal cramps, malaise, chills, fever, vasomotor disorders, pallor, and blanching of the ears and lips.

Dressler's syndrome/Harley's syndrome has been entered as a separate entity, under Lucas Anton Dressler, German physician, 1815-1896.

Bibliography:
  • J. Donath, K. Landsteiner:
    Über paroxysmale Hämoglobinurie.
    Münchener Medizinische Wochenschrift, 1904, 51: 1590-1593.

    Über Kältehämoglobinurie. Ergebnisse der Hygiene, Bakteriologie, Immunitätsforschung und experimentellen Therapie, Stuttgart, 1925, 7: 184-228.

  • Stanley Jablonski:
    Jablonski’s Dictionary of Syndromes & Eponymic diseases.
    Krieger Publishing Company, Malabar, Florida, 1991.


 
 

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