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Nothnagel's acroparesthesia

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Acroparesthesia in adults, secondary to vasomotor disorders. A syndrome of abnormal sensation in the extremities, characterized by tingling, numbness, pallor, sometimes stiffness in hands and feet, accompanied by circulatory disorders, cyanosis, blanching, and oedema. The disturbance may end in recovery or progress on to gangrene.


  • C. W. H. Nothnagel:
    Zur Lehre von den vasomotorischen Neurosen.
    Deutsches Archiv für klinische Medicin, Leipzig, 1867, 2: 173-191.

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