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Janz' syndrome

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A form of epilepsy characterized by myoclonus occurring bilaterally and especially in the upper limbs, most often between the age of 12 and 18 years, often after awakening. In Girls it may be associated with menstruation. The patient may have major and minor epileptic seizures. Probably due to a mutated gene localized on the short arm of chromosome 6.

We thank Dr. Günter Krämer, Zürich, Switzerland, for information submitted.


  • D. Janz, W. Christian:
    Impulsiv-Pétit-mal. Deutsche Zeitschrift für Nervenheilkunde, 1957, 176: 346-386.
  • B. Schmitz, T. Sander, editors:
    Juvenile Myoclonic Epilepsy. The Janz Syndrome.
    Petersfield, UK and Philadelphia, USA, Wrightson Biomedical Publishing Ltd, 2000.

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