Sudden appearance and rapid increase in size and number of seborrheic keratoses (senile warts). May be a sign of carcinoma, usually malign tumours of the gastro-intestinal tract, in high age. According to one author, the sign of Leser-Trélat is a misnomer, as they were apparently observing cherry angiomatosis in patients with cancer rather than seborrheic keratoses.
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