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Curtius' syndrome I
Also known as:
Friedreich's disease
Friedreich's syndrome
Friedreich-Auerbach disease
Steiner's syndrome
Associated persons:
Leopold Auerbach
Friedrich Curtius
Nikolaus Friedreich
Gabriel Steiner
Description:
An obsolete term for a form of hypertrophy of a part of the body with various associated disorders. It may involve a single small part of the body, such as a finger; a whole system, such as the nervous system, the muscular system, the skeletal system, or the vascular system; or half of the body with enlargement of several systems (hemigigantism). Males more frequently affected; onset from birth, but may become accentuated at puberty. Asymptomatic or variable according to signs. Frequently, ocular disorders, cutaneous lesions, adrenal cortex tumours, Wilms tumour, kidney defects, reduced capacity to thermal regulation, mental retardation, and other disorders. Some authors use the synonym Steiner's syndrome only when schizophrenia is present.
Bibliography:
- Johann Friedrich Meckel, the Younger (1781-1833):
Ueber die seitliche Asymmetrie in thierischen Körper. Anatomisch-physiologische Beobachtungen und Untersuchungen.
Halle, Renger 1822, page 147.
- Richard Barwell (1826-1916):
Case of unilateral hypertrophy of the head and face involving bones and soft parts.
Transactions of the Pathological Society of London, 1881, 32: 282-284.
- F. Curtius:
Kongenitaler partieller Riesenwuchs mit endokrinen Störungen.
Deutsches Archiv für klinische Medizin, Leipzig, 1925, 147: 310-319.
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