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Lyon's hypothesis
Also known as:
Lyon’s phenomenon
Associated persons:
Mary Frances Lyon
Description:
Hypothesis stating that only one of the two X-chromosomes is genetically active in female cells. X inactivation occurs around the 16th day of embryonic development.
Bibliography:
- M. F. Lyon:
Gene action in the X-chromosome of the mouse (Mus musculus).
Nature, London, 1961, 190: 372-373.
Theory of differential inactivation of the X-chromosome.
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